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FOXP3 抗体 (FineTest®700)

This anti-FOXP3 antibody is a 小鼠单克隆 antibody detecting FOXP3 in FACS. Suitable for 小鼠.

产品编号 ABIN7675503

发货至: 中国

Quick Overview for FOXP3 抗体 (FineTest®700) (ABIN7675503)

抗原

See all FOXP3 抗体

FOXP3 (Forkhead Box P3 (FOXP3))

适用

140
130
51
28
7
3
2
2
2
1
1
1
1

小鼠

宿主

小鼠

克隆类型

单克隆

标记

93
17
14
13
7
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1

This FOXP3 antibody is conjugated to FineTest®700

应用范围

118
89
59
40
39
27
27
21
18
16
10
8
7
6
4
3
2
2
2
2
1
1
1

Flow Cytometry (FACS)

克隆位点

3G3

Discover our top product FOXP3 Primary Antibody

原理

FineTest®700 Anti-Mouse Foxp3 Antibody

亚型

IgG1, kappa
anti-Forkhead Box P3 (FOXP3) (AA 190-412) antibody
FOXP3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 小鼠 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 297-431) antibody
FOXP3 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 4F12A2 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
Verified FOXP3 适用: 人 WB, FACS, ELISA, IHC, IF, ICC 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (N-Term) antibody
FOXP3 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马, 犬, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 1-431) antibody
FOXP3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) antibody (APC)
FOXP3 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal 3G3 APC

anti-Forkhead Box P3 (FOXP3) (AA 101-431) antibody
FOXP3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze / thaw cycles.

储存条件

4 °C

储存方法

2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

有效期

12 months
抗原

FOXP3 (Forkhead Box P3 (FOXP3))

别名

Foxp3

背景

Synonyms: Forkhead box protein P3|Foxp3|IPEX|JM2
Background: Foxp3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of Foxp3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. Foxp3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in 'scurfy' mice. Overexpression of Foxp3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of Foxp3 have been reported: one (Foxp3) corresponding to the canonical full-length sequence, the other (Foxp3 δ2) lacking exon 2.

分子量

0

UniProt

Q99JB6

途径

Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation

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